Edward L. Murphy, Jr., M.D., M.P.H
Senior Investigator, Epidemiology (UCSF)
Profile
Edward L. Murphy, M.D., M.P.H., is an internal medicine physician and epidemiologist with a research career focused on viral and clinical epidemiology. During his fellowship at the National Cancer Institute under Drs. William Blattner and Robert Gallo, he did field work on the epidemiology of HTLV-1 in Jamaica, West Indies and followed this with major discoveries about HTLV-1 and HTLV-2. After joining the faculty at UCSF in 1988, his research focus expanded to the epidemiology of other transfusion-transmitted viruses including HIV and hepatitis B and C viruses. More recently, he has developed a program in global transfusion safety including transfusion-related HIV research and training programs in Brazil and South Africa in conjunction with the NHLBI REDS program.
- Senior Investigator, Vitalant Research Institute, San Francisco
- Professor in Residence, UCSF Department of Laboratory Medicine
- Directeur du Cours, Institut Pasteur, Paris, France
- BS, Marine Biology, Massachusetts Institute of Technology, Cambridge, MA
- MD, Stanford University School of Medicine, Stanford, CA
- MPH, University of California, Berkeley, School of Public Health, Berkeley, CA
- Residency in Internal Medicine, Boston University Hospital, Boston, MA
- Medical Staff Fellowship, National Cancer Institute, Bethesda, MD
Nareg Roubinian, MD, MPHTM
Clinical Investigator
Nareg Roubinian, MD, MPHTM, is a clinical investigator with appointments at BSRI, the Kaiser Permanente Division of Research, and the University of California, San Francisco (UCSF). Dr. Roubinian received his BS from the University of California, Berkeley and his MD from the University of Vermont College of Medicine. He completed his residency in internal medicine at Washington University in St. Louis, and his fellowship in pulmonary and critical care medicine at UCSF.
Read more about Nareg Roubinian, MD, MPHTM
Daniel Hindes, BS
Research Associate II
Anne Guiltinan, MA, LMFT
Senior Project Manager
Zhanna Kaidarova, MBA
Statistician II
- Senior Investigator, Vitalant Research Institute, San Francisco
- Professor in Residence, UCSF Department of Laboratory Medicine
- Directeur du Cours, Institut Pasteur, Paris, France
- BS, Marine Biology, Massachusetts Institute of Technology, Cambridge, MA
- MD, Stanford University School of Medicine, Stanford, CA
- MPH, University of California, Berkeley, School of Public Health, Berkeley, CA
- Residency in Internal Medicine, Boston University Hospital, Boston, MA
- Medical Staff Fellowship, National Cancer Institute, Bethesda, MD
Nareg Roubinian, MD, MPHTM
Clinical Investigator
Nareg Roubinian, MD, MPHTM, is a clinical investigator with appointments at BSRI, the Kaiser Permanente Division of Research, and the University of California, San Francisco (UCSF). Dr. Roubinian received his BS from the University of California, Berkeley and his MD from the University of Vermont College of Medicine. He completed his residency in internal medicine at Washington University in St. Louis, and his fellowship in pulmonary and critical care medicine at UCSF.
Read more about Nareg Roubinian, MD, MPHTM
Daniel Hindes, BS
Research Associate II
Anne Guiltinan, MA, LMFT
Senior Project Manager
Zhanna Kaidarova, MBA
Statistician II
Research Interests
Since 1989, Dr. Murphy has been the P.I. of the San Francisco site of the multi-center NHLBI Recipient Epidemiology and Donor Surveillance (REDS) study, whose purpose is to perform epidemiological studies to monitor and reduce infectious and non-infectious risks in blood donors and transfused patients. A 10-year NHLBI Mid-Career Investigator Award (K24) and the NHLBI REDS International Program have funded an international research and training program for 250 junior scientists from Latin America, South Africa and francophone Africa. Finally, Dr. Murphy established a multicenter (five U.S. cities) cohort study of almost 550 HTLV-1 and -2 infected blood donors and 800 age-, sex- and race-matched controls. The cohort, with almost 20 years of biennial follow-up, is recognized for major findings in the epidemiology, virology and pathophysiology of HTLV-1 and -2 infection.
Since 1989, Dr. Murphy has been the P.I. of the San Francisco site of the multi-center NHLBI REDS studies of transfusion safety research. Since 2011, Dr. Murphy has been principal investigator on two large, 7-year contracts for the NHLBI REDS-III program: the UCSF/BSRI Domestic center and the UCSF/South African National Blood Service International center. REDS started with a focus on measuring the epidemiology of transfusion-transmitted viruses but has expanded its scope to include several themes of transfusion safety research.
A 10-year NHLBI Mid-Career Investigator Award (K24) and the REDS-III International program have funded Dr. Murphy’s activities in global transfusion safety research and training. The REDS-III South Africa program is focused on HIV risk factors and early treatment while studies in francophone Africa are devoted to various aspects of blood collection, viral testing and utilization. A key component is knowledge transfer to build a new generation of transfusion medicine clinical researchers in Africa.
Dr. Murphy began his HTLV epidemiology research during his fellowship at the NCI, and continued it at UCSF and BSRI with a multicenter (five U.S. cities) cohort study of almost 550 HTLV-1 and -2 infected blood donors and 800 age-, sex- and race-matched controls. The cohort, established in 1990-1992, completed almost 20 years of biennial follow-up and is recognized for major findings in the HTLV field. Its biospecimen repository is still used in translational studies of HTLV biology and pathogenesis by our lab and international collaborators.