The Viral Reference Laboratory and Repository Core leads the development and operations of the BSRI Biorepository is a comprehensive biobank that supports basic and translational research of internal, domestic and international collaborators. The Core maintains repositories for a number of domestic and international studies, manages study operations and sample testing, and performs pilot studies for study protocol development and research. The VRLRC has expertise in study design, execution and operations, and provides these services through scientific collaboration and consultation. Key functions of the Core are to collect, process and store well-characterized biospecimens, access the comprehensive Biorepository for the development and validation of screening and diagnostic assays, and enable virological and immunological studies. The department serves as liaison to and interfaces with internal and external investigators on both small and large multicenter studies to manage and access samples and to coordinate biospecimen collection and processing. It also provides oversight and management of operations of the biorepository.