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VRI to participate in a large seven-year blood transfusion research program

5/8/2019

NHLBI of the NIH awarded VRI multiple seven-year contracts for the next evolution of Transfusion Medicine research that will be conducted under REDS. This is the fourth phase (REDS-IV-P) of funding for the REDS programs that VRI/BSRI has received from NHLBI since 1989, making the research institute a 30-year partner in the REDS project history.

Red blood cells' shelf life might depend on donor's genes

1/9/2019

Dr. Michael Busch principal investigator for the RBC-Omics Study, and his partners at RTI and NHLBI provided a summary of the study’s early findings. The study investigates genetic variations in donors and its’ effects on blood storage and cell function. These findings might open the door to a future in which donor genotype is taken into account. Read more about the research here.

Pillai discusses new era for HIV research

11/30/2018

In a recent article published by The Guardian, Dr. Pillai discusses how HIV-infected cells are able to ‘hide’ in the body, and are now being identified and destroyed in a novel strategy. This strategy for finding and destroying this last reservoir of hiding cells could be the key –or holy grail – to eradicating the virus. Read more about the research here.

Tran Receives AABB Top Poster Award

10/12/2018

Dr. Johnson Tran, of Dr. Jackman's lab, received the award for Top Poster at the annual AABB Conference held in Boston. The presentation abstract titled, “Pathogen Reduction of Platelet Rich Plasma Abrogates T Cell Alloresponse in Mice” demonstrated how allogeneic CD4+ and CD8+ T cell activation and effector responses were significantly diminished after pathogen reduction with UV+R treatment. Read more about the AABB Conference here.

CHIKV inhibited by neutralizing antibodies

9/25/2018

In the recent issue of Cell Host & Microbe, Dr. Jin et al report that some anti-CHIKV neutralizing mAbs inhibit the budding step of the CHIKV replication cycle by inducing crosslinking of viral GPs at the PM. It is demonstrated that anti-CHIKV neutralizing mAbs crosslink viral GPs at the PM of infected cells, preventing envelopment of nucleocapsids and causing the accumulation of arrested nucleocapsids in the cytosol. Watch here.

Roubinian Receives ECDHM Best Oral Abstract Award

9/7/2018

Dr. Roubinian receives the award for Best Oral Abstract Presentation at the European Donor Health and Outcomes Congress in Copenhagen.   The presentation abstract titled, “Influence of Donor, Component, and Recipient Factors on Efficacy of Erythrocyte Transfusions” examined the role of blood donor, component and transfusion recipient factors on hemoglobin increments following red blood cell transfusion. Read more about the ECDHM Congress here.

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